NOMIS

NOTE: NOMIS requires Freesurfer 6.0 outputs. For more detail see Freesurfer.

To derive norm scores from Freesurfer 5.3, see the document below.

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Freesurfer Norm Scores.docx

Downloading NOMIS

LogoGitHub - medicslaboratory/NOMIS: NOrmative Morphometry Image Statistics (NOMIS) for FreeSurfer 6.0GitHub

Download NOMIS from the github link above

Setting up a NOMIS conda environment

create a conda environment:

conda create -n "nomis" python==3.7.4

install dependencies

conda activate nomis
pip install argparse==1.1
pip install nibabel==2.5.1
pip install numpy==1.17.2
pip install pandas==0.25.1
pip install pickle4
pip install scikit-learn==0.21.3

Running NOMIS

Create a setup file. This is a .csv file with five columns: id, age, sex, manufacturer, and mfs.

  • id: subject ID as it appears on in Freesurfer outputs

  • age: can be a whole number or a decimal

  • sex: M or F, uncertain of how this should be marked for people who identify as a gender they were not assigned at birth

  • manufacturer: manufacturer of the MRI machine (for our purposes, usually Seimens)

  • mfs: manufacturer field strength (for our purposes, usually 3)

See example below:

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NOMIS_setup.csv

Run NOMIS using the following command structure:

conda activate nomis
python [path to nomis folder]/nomis.py -csv [path to setup file] -s [path to FS outputs] -o [path to nomis outputs]

NOMIS Outputs

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